KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHTF18
All Species:
36.06
Human Site:
S588
Identified Species:
61.03
UniProt:
Q8WVB6
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8WVB6
NP_071375.1
975
107383
S588
D
Q
R
R
G
L
F
S
V
W
Q
E
V
F
Q
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001087813
975
107675
S588
D
Q
R
R
G
L
F
S
V
W
Q
E
V
F
Q
Dog
Lupus familis
XP_547205
952
105405
S552
D
Q
R
K
G
L
F
S
V
W
Q
E
I
F
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8BIW9
969
108119
S582
D
Q
R
K
G
L
F
S
V
W
Q
E
V
F
Q
Rat
Rattus norvegicus
NP_001099243
968
107973
S581
D
Q
R
K
G
L
F
S
V
W
Q
E
V
F
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519056
506
55652
R205
V
T
S
T
D
G
T
R
V
Y
L
V
M
K
D
Chicken
Gallus gallus
XP_414833
951
106607
S566
D
Q
N
K
G
L
F
S
I
W
Q
E
I
F
Q
Frog
Xenopus laevis
Q6NU40
1000
113204
S607
D
Q
N
K
G
L
F
S
V
W
Q
E
I
F
Q
Zebra Danio
Brachydanio rerio
NP_001103572
957
108656
S583
D
Q
N
K
G
L
F
S
V
W
Q
E
I
F
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_787969
993
111731
A630
D
R
H
Q
G
L
F
A
V
W
D
A
I
F
R
Honey Bee
Apis mellifera
XP_001122463
755
86984
S455
Q
Y
M
G
G
I
N
S
K
D
N
L
S
F
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780624
1005
112781
T609
D
Q
H
K
S
L
Y
T
V
W
Q
Q
L
F
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_171966
954
107988
R564
I
G
S
Q
V
V
G
R
K
D
M
S
K
S
L
Baker's Yeast
Sacchar. cerevisiae
P49956
741
84355
F440
D
R
I
L
Q
G
C
F
N
I
F
P
Y
V
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
94.5
73
N.A.
76
77.2
N.A.
20.2
53.7
53.4
46.6
N.A.
32.4
27.8
N.A.
34.6
Protein Similarity:
100
N.A.
95.9
79.6
N.A.
81.7
82.7
N.A.
29.8
68.7
71
63.3
N.A.
52.5
45.3
N.A.
54.1
P-Site Identity:
100
N.A.
100
86.6
N.A.
93.3
93.3
N.A.
6.6
73.3
80
80
N.A.
46.6
20
N.A.
53.3
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
20
93.3
93.3
93.3
N.A.
80
26.6
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
22
21.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40
39.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
8
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% C
% Asp:
79
0
0
0
8
0
0
0
0
15
8
0
0
0
8
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
58
0
0
0
% E
% Phe:
0
0
0
0
0
0
65
8
0
0
8
0
0
79
0
% F
% Gly:
0
8
0
8
72
15
8
0
0
0
0
0
0
0
0
% G
% His:
0
0
15
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
8
0
0
8
0
0
8
8
0
0
36
0
0
% I
% Lys:
0
0
0
50
0
0
0
0
15
0
0
0
8
8
8
% K
% Leu:
0
0
0
8
0
72
0
0
0
0
8
8
8
0
8
% L
% Met:
0
0
8
0
0
0
0
0
0
0
8
0
8
0
0
% M
% Asn:
0
0
22
0
0
0
8
0
8
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% P
% Gln:
8
65
0
15
8
0
0
0
0
0
65
8
0
0
65
% Q
% Arg:
0
15
36
15
0
0
0
15
0
0
0
0
0
0
8
% R
% Ser:
0
0
15
0
8
0
0
65
0
0
0
8
8
8
0
% S
% Thr:
0
8
0
8
0
0
8
8
0
0
0
0
0
0
0
% T
% Val:
8
0
0
0
8
8
0
0
72
0
0
8
29
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
72
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
8
0
0
8
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _